Cognitive Remediation Services for People with Schizophrenia: Considerations for Health Service Practitioners


Ahmed, A. O., Hansen, M. C., & Lindenmayer, J. P. (2018). Cognitive remediation services for people with schizophrenia: Considerations for health service practitioners. Journal of Health Service Psychology, 44, 80–89.


Cognitive deficits are a prominent feature of many psychiatric disorders and are predictors of decreased functioning, quality of life, and treatment response. Cognitive remediation focuses on improving cognitive skills through repeated practice and strategy learning. In people with schizophrenia, cognitive remediation is associated with improvements in cognition and psychosocial functions. This article provides an overview of cognitive remediation and some considerations for developing a cognitive remediation service in a treatment setting.

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Ahmed, A. O., Hunter, K. M., van Houten, E. G., Monroe, J. M., & Bhat, I. A. (2014). Cognition and Other Targets for the Treatment of Aggression in People with Schizophrenia. Annals of Psychiatry and Mental Health2(1), 100–111.

Ahmed, A. O., Mantini, A. M., Fridberg, D. J., & Buckley, P. F. (2015). Brain-derived neurotrophic factor (BDNF) and neurocognitive deficits in people with schizophrenia: a meta-analysis. Psychiatry Research226(1), 1–13.

Bowie, C. R., McGurk, S. R., Mausbach, B., Patterson, T. L., & Harvey, P. D. (2012). Combined cognitive remediation and functional skills training for schizophrenia: effects on cognition, functional competence, and real-world behavior. American Journal of Psychiatry169(7), 710–718.

Fisher, M., Mellon, S. H., Wolkowitz, O., & Vinogradov, S. (2016). Neuroscience-informed Auditory Training in Schizophrenia: A Final Report of the Effects on Cognition and Serum Brain-Derived Neurotrophic Factor. Schizophrenia Research. Cognition3, 1–7.

Green, M. F., & Harvey, P. D. (2014). Cognition in schizophrenia: Past, present, and future. Schizophrenia Research. Cognition1(1), e1–e9.

Green, M. F., & Leitman, D. I. (2008). Social Cognition in Schizophrenia. Schizophrenia Bulletin34(4), 670–672.

Green, M. F., Nuechterlein, K. H., Gold, J. M., Barch, D. M., Cohen, J., Essock, S., … Marder, S. R. (2004). Approaching a consensus cognitive battery for clinical trials in schizophrenia: the NIMH-MATRICS conference to select cognitive domains and test criteria. Biological Psychiatry56(5), 301–307.

Horton, H. K., & Silverstein, S. M. (2008). Social cognition as a mediator of cognition and outcome among deaf and hearing people with schizophrenia. Schizophrenia Research105(1–3), 125–137.

Jabben, N., Arts, B., van Os, J., & Krabbendam, L. (2010). Neurocognitive functioning as intermediary phenotype and predictor of psychosocial functioning across the psychosis continuum: studies in schizophrenia and bipolar disorder. Journal of Clinical Psychiatry71(6), 764–774.

Keefe, R. S. E., Harvey, P. D., Goldberg, T. E., Gold, J. M., Walker, T. M., Kennel, C., & Hawkins, K. (2008). Norms and standardization of the Brief Assessment of Cognition in Schizophrenia (BACS). Schizophrenia Research102(1–3), 108–115.

Kern, R. S., Nuechterlein, K. H., Green, M. F., Baade, L. E., Fenton, W. S., Gold, J. M., … Marder, S. R. (2008). The MATRICS Consensus Cognitive Battery, Part 2: Co-Norming and Standardization. American Journal of Psychiatry165(2), 214–220.

Kern, R.S., Gold, J.M., Dickinson, D., Green, M.F., Nuechterlein, K.H., Baade, L.E., … Marder SR. (2011). The MCCB impairment profile for schizophrenia outpatients: results from the MATRICS psychometric and standardization study. Schizophrenia Research, 126, 124-131. doi: 10.1016/j.schres.2010.11.008.

Keshavan, M. S., Vinogradov, S., Rumsey, J., Sherrill, J., & Wagner, A. (2014). Cognitive training in mental disorders: update and future directions. American Journal of Psychiatry171(5), 510–522.

Kremen, W.S., Seidman, L.J., Faraone, S.V., Toomey, R., & Tsuang, M.T. (2000). The paradox of normal neuropsychological function in schizophrenia. Journal of Abnormal Psychology, 109(4), 743-752.

Kolb, B. & Teskey, G.C. (2012). Age, experience, injury, and the changing brain. Developmental Psychobiology, 54(3), 311-325.

Kurtz, M. M., & Richardson, C. L. (2011). Social Cognitive Training for Schizophrenia: A Meta-Analytic Investigation of Controlled Research. Schizophrenia Bulletin, sbr036.

Lindenmayer,  J.P., Fregenti, S., Kang, G., Ozog, V., Ljuri, I., Khan, A., Goldring, A., & McGurk, S.R. (2017). The relationship of cognitive improvement after cognitive remediation with social functioning in patients with schizophrenia and severe cognitive deficits. Schizophrenia Research, 185,154-160.

Mancuso, F., Horan, W. P., Kern, R. S., & Green, M. F. (2011). Social cognition in psychosis: multidimensional structure, clinical correlates, and relationship with functional outcome. Schizophrenia Research125(2–3), 143–151.

Medalia, A. & Bowie, C.R. (2016). Cognitive Remediation to Improve Functional Outcomes. Oxford University Press: New York.

Medalia, A., & Choi, J. (2009). Cognitive remediation in schizophrenia. Neuropsychology Review19(3), 353–364.

Medalia, A., Revheim, N., & Casey, M. (2001). The remediation of problem-solving skills in schizophrenia. Schizophrenia Bulletin27(2), 259–267.

Medalia, A., Revheim, N., & Herlands, T. (2009). Cognitive Remediation for Psychological Disorders: Therapist Guide. Oxford University Press: New York

Medalia, A., & Richardson, R. (2005). What predicts a good response to cognitive remediation interventions? Schizophrenia Bulletin, 31(4), 942-953. doi:10.1093/schbul/sbi045

Medalia, A., Saperstein, A. M., Hansen, M. C., & Lee, S. (2016). Personalised treatment for cognitive dysfunction in individuals with schizophrenia spectrum disorders. Neuropsychological Rehabilitation, 1-12. doi:10.1080/09602011.2016.1189341

Ramsay, I. S., & MacDonald, A. W. (2015). Brain correlates of cognitive remediation in schizophrenia: activation likelihood analysis shows preliminary evidence of neural target engagement. Schizophrenia Bulletin41(6), 1276–1284.

Sablier, J., Stip, E., & Franck, N. (2009). [Cognitive remediation and cognitive assistive technologies in schizophrenia]. L’Encephale35(2), 160–167.

Strauss, G. P., & Gold, J.M. (2012). A new perspective on aanhedonia in schizophrenia.American Journal of Psychiatry, 169(4), 364-373.

Strauss, G. P., Whearty, K. M., Frost, K. H., & Carpenter, W. T. (2016). An affective neuroscience model of impaired approach motivation in schizophrenia. Nebraska Symposium on Motivation, 63, 159-203.

Trivedi, J. K. (2006). Cognitive deficits in psychiatric disorders: Current status. Indian Journal of Psychiatry48(1), 10–20.

van Passel, B., Danner, U., Dingemans, A., van Furth, E., Sternheim, L., van Elburg, A., … Cath, D. (2016). Cognitive remediation therapy (CRT) as a treatment enhancer of eating disorders and obsessive compulsive disorders: study protocol for a randomized controlled trial. BMC Psychiatry16(1), 393.

Velligan, D. I., Kern, R. S., & Gold, J. M. (2006). Cognitive rehabilitation for schizophrenia and the putative role of motivation and expectancies. Schizophrenia Bulletin32(3), 474–485.

Vinogradov, S., Fisher, M., & de Villers-Sidani, E. (2012). Cognitive training for impaired neural systems in neuropsychiatric illness. Neuropsychopharmacology, 37(1), 43-76. doi:10.1038/npp.2011.251

Vinogradov, S., Fisher, M., Warm, H., Holland, C., Kirshner, M. A., & Pollock, B. G. (2009). The cognitive cost of anticholinergic burden: decreased response to cognitive training in schizophrenia. American Journal of Psychiatry166(9), 1055–1062.

Wykes, T., Huddy, V., Cellard, C., McGurk, S. R., & Czobor, P. (2011). A meta-analysis of cognitive remediation for schizophrenia: methodology and effect sizes. American Journal of Psychiatry168(5), 472–485.

Zhuo, C., Zhu, J., Wang, C., Qu, H., Ma, X., Tian, H., … Qin, W. (2017). Brain structural and functional dissociated patterns in schizophrenia. BMC Psychiatry17(1), 45.

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